Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | AGPAT2 | O15120 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 7/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.44 |
| ▸ | CASP3 | P42574 | 3/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28689683 | 0.84 | MEN1 (0.48) | TP53MAPTRAB9ANPC1MAPK1 | |
| SCHEMBL11401593 | 0.81 | RAB9A (0.47) | TP53MAPTRAB9ANPC1KDM4E | |
| SCHEMBL22282700 | 0.77 | HIF1A (0.36) | NPC1MAPK1KDM4EALDH1A1 | |
| SCHEMBL13486502 | 0.75 | HPGD (0.58) | TP53MAPTRAB9ANPC1MAPK1 | |
| SCHEMBL24766804 | 0.73 | GAA (0.49) | TP53MAPTRAB9ANPC1MAPK1 | |
| SCHEMBL27492487 | 0.73 | KMT2A (0.50) | TP53MAPTRAB9ANPC1MAPK1 | |
| SCHEMBL3611112 | 0.72 | AGPAT2 (0.49) | TP53MAPTRAB9ANPC1MAPK1 | |
| SCHEMBL28661658 | 0.71 | CEPT1 (0.41) | TP53MAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL11333951 | 0.71 | AGPAT2 (0.47) | TP53MAPTRAB9ANPC1MAPK1 | |
| SCHEMBL14925499 | 0.71 | MAPT (0.49) | TP53MAPTRAB9ANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113818033-B | Electrochemical synthesis method of 2-substituted benzoxazole derivative | 诚达药业股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-113818033-A | Electrochemical synthesis method of 2-substituted benzoxazole derivative | 诚达药业股份有限公司 | 2021-12-21 | — | — | CN | disclosed |