Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571160 | 0.92 | IDO1 (0.53) | MAOBMAPTALDH1A1HTR2ARAB9A | |
| SCHEMBL13777552 | 0.83 | MAPT (0.46) | MAOBPLA2G4BMAPTHTR2A | |
| SCHEMBL28621039 | 0.82 | CA12 (0.76) | MAOBPLA2G4BCA12CA1CA2 | |
| SCHEMBL2359708 | 0.81 | THRB (0.58) | MAOBCYP1A2 | |
| SCHEMBL26185836 | 0.81 | MAOB (0.68) | MAOBPLA2G4BCA12CA1CA2 | |
| SCHEMBL11274311 | 0.79 | IDO1 (0.56) | MAOBMAPTALDH1A1KMT2AHTR2A | |
| SCHEMBL8948959 | 0.79 | MAOB (0.70) | MAOBPLA2G4BCA12CA1CA2 | |
| SCHEMBL9185772 | 0.78 | IDO1 (0.54) | MAOBMAPTALDH1A1HTR2ARAB9A | |
| SCHEMBL6326722 | 0.78 | CA12 (0.66) | MAOBPLA2G4BCA12CA1CA2 | |
| SCHEMBL4759195 | 0.77 | MAOB (0.68) | MAOBPLA2G4BCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113817164-B | Hypoxic sensitive drug carrier polymer and preparation method and application thereof | 北京化工大学 | 2022-11-29 | — | — | CN | claimed |
| CN-113817164-A | Hypoxic sensitive drug carrier polymer and preparation method and application thereof | 北京化工大学 | 2021-12-21 | — | — | CN | claimed |
| CN-113817164-B | Hypoxic sensitive drug carrier polymer and preparation method and application thereof | 北京化工大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-113817164-A | Hypoxic sensitive drug carrier polymer and preparation method and application thereof | 北京化工大学 | 2021-12-21 | — | — | CN | disclosed |