Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 7/20 | 0.48 |
| ▸ | HTR2A | P28223 | 6/20 | 0.48 |
| ▸ | HTR1A | P08908 | 5/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28699857 | 0.96 | ALDH1A1 (0.56) | ALDH1A1TRIM24TRIM33HSD17B10KDM4E | |
| SCHEMBL19057548 | 0.91 | ALDH1A1 (0.61) | ALDH1A1TRIM24TRIM33HSD17B10KDM4E | |
| SCHEMBL28694827 | 0.89 | ALDH1A1 (0.55) | ALDH1A1TRIM24TRIM33HSD17B10KDM4E | |
| SCHEMBL28703960 | 0.86 | TRIM24 (0.55) | ALDH1A1TRIM24TRIM33HSD17B10KDM4E | |
| SCHEMBL377522 | 0.84 | ALDH1A1 (0.63) | ALDH1A1TRIM24TRIM33KDM4ESMN1; SMN2 | |
| SCHEMBL23922764 | 0.83 | ALDH1A1 (0.58) | ALDH1A1TRIM24TRIM33HSD17B10KDM4E | |
| SCHEMBL13103801 | 0.82 | DRD2 (0.56) | ALDH1A1HSD17B10KDM4EDRD2HTR2A | |
| SCHEMBL10900857 | 0.81 | KDM4E (0.67) | ALDH1A1TRIM24TRIM33KDM4ESMN1; SMN2 | |
| SCHEMBL19297522 | 0.81 | SLC6A2 (0.60) | HSD17B10KDM4EDRD2HTR2AHTR1A | |
| SCHEMBL23097718 | 0.81 | DRD2 (0.68) | HSD17B10KDM4EDRD2HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563092-B | 2-phenylimidazo [4,5-B ] pyridin-7-amine derivatives useful as inhibitors of the activity of the mammalian tyrosine kinase ROR1 | 坎塞拉有限公司 | 2021-09-14 | — | — | CN | disclosed |