Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29460122 | 1.00 | HSP90AA1 (0.39) | HSP90AA1BRD4HSP90AB1ACHEHDAC8 | |
| SCHEMBL26447852 | 0.87 | HSP90AA1 (0.46) | HSP90AA1BRD4HSP90AB1 | |
| SCHEMBL24477130 | 0.84 | BRD4 (0.44) | HSP90AA1BRD4HSP90AB1ACHEKDM4E | |
| SCHEMBL16582337 | 0.84 | ALDH1A1 (0.37) | HSP90AA1HSP90AB1ACHEHDAC8HDAC1 | |
| SCHEMBL14780794 | 0.84 | HSP90AA1 (0.54) | HSP90AA1HSP90AB1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL22541270 | 0.83 | BRD4 (0.43) | HSP90AA1BRD4HSP90AB1ACHEKDM4E | |
| SCHEMBL22541229 | 0.81 | BRD4 (0.47) | HSP90AA1BRD4HSP90AB1MEN1KMT2A | |
| SCHEMBL22541290 | 0.80 | BRD4 (0.41) | HSP90AA1BRD4HSP90AB1KDM4EALDH1A1 | |
| SCHEMBL24334860 | 0.80 | BRD4 (0.40) | HSP90AA1BRD4HSP90AB1KDM4EALDH1A1 | |
| SCHEMBL24321631 | 0.78 | BRD4 (0.40) | HSP90AA1BRD4HSP90AB1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113939516-B | Methods and compositions for targeting protein degradation | 珃诺生物医药科技(杭州)有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-113939516-A | Methods and compositions for targeted protein degradation | 珃诺生物医药科技(杭州)有限公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-113924123-A | Methods and compositions for targeted protein degradation | 珃诺生物医药科技(杭州)有限公司 | 2022-01-11 | — | — | CN | disclosed |