SCHEMBL286907

SCHEMBL286907

O=C(Cl)C(Cl)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.48
SRC P12931 1/20 0.48
TSHR P16473 1/20 0.48
LMNA P02545 4/20 0.46
MAPK1 P28482 1/20 0.46
CES2 O00748 2/20 0.44
CES1 P23141 2/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HPGD P15428 1/20 0.42
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1173291 1.00 CYP2D6 (0.48) CYP2D6SRCTSHRLMNAMAPK1
SCHEMBL9823813 1.00 CYP2D6 (0.48) CYP2D6SRCTSHRLMNAMAPK1
SCHEMBL8698888 0.95 CYP2D6 (0.44) CYP2D6SRCTSHRLMNAMAPK1
SCHEMBL664900 0.82 SRC (0.56) CYP2D6SRCTSHRLMNAMAPK1
SCHEMBL5325296 0.82 SRC (0.56) CYP2D6SRCTSHRLMNAMAPK1
SCHEMBL9181806 0.82 CYP2D6 (0.50) CYP2D6SRCTSHRLMNAMAPK1
Hydrochloric Acid SCHEMBL6334096 0.80 SRC (0.54) CYP2D6SRCTSHRLMNAMAPK1
Ammonia Solution, Strong SCHEMBL38660871 0.80 SRC (0.54) CYP2D6SRCTSHRLMNAMAPK1
SCHEMBL6960854 0.80 CYP2D6 (0.48) CYP2D6SRCTSHRLMNAMAPK1
SCHEMBL1829395 0.79 TSHR (0.52) CYP2D6SRCTSHRLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 620 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431424-A Silicon oxime ester-containing photoinitiator, preparation method and application thereof 常州强力先端电子材料有限公司 2025-02-14 CN claimed
CN-112851547-B Fluorene oxime ester compound, preparation method thereof and photosensitive resin composition 常州强力先端电子材料有限公司 2024-06-07 CN claimed
CN-117986231-A Oxime ester photoinitiator, preparation method and application thereof 常州强力电子新材料股份有限公司 2024-05-07 CN claimed
CN-117986232-A Oxime ester photoinitiator, preparation method and application thereof 常州强力电子新材料股份有限公司 2024-05-07 CN claimed
CN-116199616-A Modified oxime ester compound, preparation method thereof and photo-curing composition 常州强力电子新材料股份有限公司 2023-06-02 CN claimed
CN-116199617-A Oxime ester compound, preparation method thereof and photo-curing composition 常州强力电子新材料股份有限公司 2023-06-02 CN claimed
CN-112851547-A Fluorenoxime ester compound, preparation method thereof and photosensitive resin composition 常州强力先端电子材料有限公司 2021-05-28 CN claimed
CN-109734720-A 18F marks DPA-714 analog derivative and its preparation method and application 中国人民解放军东部战区总医院 2019-05-10 CN claimed
US-10220118-B2 Self-replenishing boundary lubrication in hydrogels using zwitterionic polymers SYRACUSE UNIVERSITY (US) 2019-03-05 US claimed
CN-108863774-A A kind of 2,4 dichloro benzene chloroacetic chloride synthetic method 石家庄市绿丰化工有限公司 2018-11-23 CN claimed
US-20170112970-A1 SELF-REPLENISHING BOUNDARY LUBRICATION IN HYDROGELS USING ZWITTERIONIC POLYMERS SYRACUSE UNIVERSITY (US) 2017-04-27 US claimed
CN-103420823-B The synthetic method of ��-chloro-4 fluorophenyl benzyl ketones 南京欧信医药技术有限公司 2016-06-08 CN claimed
CN-103254027-B One prepares the method for 1,2-diphenyl propylene compound SINOCHEM CORPORATION (CN) 2015-09-23 CN claimed
US-20150203639-A1 POLYTHIOPHENE STAR COPOLYMER CAPABLE OF BEING SELF-DOPED BY EXTERNAL STIMULUS, A METHOD FOR PRODUCING THE SAME, A CONDUCTIVE THIN FILM USING THE SAME, AND A METHOD FOR PRODUCING THE CONDUCTIVE THIN FILM KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-07-23 US claimed
EP-1323714-B1 1,3-selenazole derivatives and their use as anticancer drugs or as agrochemicals PRESIDENT OF GIFU UNIVERSITY (JP) 2006-09-20 EP claimed
US-20030158239-A1 Novel 1,3-selenazolin derivatives and process for preparing the same GIFU UNIVERSITY (JP) 2003-08-21 US claimed
EP-1323714-A1 1,3-selenazole derivatives and their use as anticancer drugs or as agrochemicals President of Gifu University (JP) 2003-07-02 EP claimed
US-4072710-A FROM SILYL ESTER AND THIONYL CHLORIDE PALOMO COLL A L 1978-02-07 US claimed
JP-63057522-A None JP disclosed
US-3971771-A DYES FOR POLYESTERS CIBA-GEIGY AG (CH) 1976-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030158239-A1 Novel 1,3-selenazolin derivatives and process for preparing the same SELENOI, SCLY, SULT1A1 CYP2D6 716/4885SRC 2346/4885TSHR 1372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.