Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 15/20 | 0.64 |
| ▸ | NTRK3 | Q16288 | 10/20 | 0.64 |
| ▸ | NTRK2 | Q16620 | 10/20 | 0.64 |
| ▸ | CSF1R | P07333 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | KIT | P10721 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 3/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29387760 | 1.00 | NTRK1 (0.64) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL28690936 | 1.00 | NTRK1 (0.64) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL28933419 | 0.92 | NTRK1 (0.72) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL28933421 | 0.92 | NTRK1 (0.72) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL28684861 | 0.91 | NTRK1 (0.64) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL28684857 | 0.91 | NTRK1 (0.64) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL28686141 | 0.90 | NTRK1 (0.58) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL28686143 | 0.90 | NTRK1 (0.58) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL30792166 | 0.89 | NTRK1 (0.61) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL28706609 | 0.89 | NTRK1 (0.61) | NTRK1NTRK3NTRK2CSF1RPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072387-A | Indazole compound and medicinal composition and application thereof | 暨南大学 | 2022-02-18 | — | — | CN | disclosed |