Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2873358 | 0.92 | MEN1 (0.47) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL2875356 | 0.88 | KMT2A (0.50) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL2878353 | 0.85 | MEN1 (0.47) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL2873172 | 0.84 | ESR1 (0.43) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL2872281 | 0.80 | ESR1 (0.44) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL2878341 | 0.79 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1TUBB4ATUBB | |
| SCHEMBL2869092 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL2873468 | 0.77 | ESR1 (0.43) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL2876517 | 0.75 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL2878396 | 0.74 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066628-B1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | SANOFI AVENTIS (FR) | 2010-10-20 | — | — | EP | disclosed |