Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348481 | 0.85 | MEN1 (0.59) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL8462360 | 0.85 | TSHR (0.62) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL21473833 | 0.85 | TSHR (0.62) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL343011 | 0.83 | MAPT (0.77) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL27411599 | 0.81 | MEN1 (0.60) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL4776752 | 0.81 | KMT2A (0.56) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL11777806 | 0.81 | MEN1 (0.59) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL13175570 | 0.79 | ALDH1A1 (0.66) | KMT2AMAPTTSHRALDH1A1CYP3A4 | |
| SCHEMBL7880423 | 0.77 | MEN1 (0.56) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL20483494 | 0.76 | ESR1 (0.79) | MEN1KMT2AMAPTPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884083-B | Benzo [ B ] furans as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2022-02-25 | — | — | CN | disclosed |