SCHEMBL2869217

SCHEMBL2869217

Cc1ccc(C(c2ccc(C)cc2)=[Zr](C2=CC=CC2)C2c3cc(C(C)(C)C)ccc3-c3ccc(C(C)(C)C)cc32)cc1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL811378 0.99 NPC1 (0.32) NPC1MAPTRAB9ATSHR
SCHEMBL6228825 0.94 MEN1 (0.30) MAPT
SCHEMBL6231459 0.93 NPC1 (0.32) NPC1MAPTRAB9ATSHR
Hydrochloric Acid SCHEMBL811711 0.93
SCHEMBL2861724 0.91 NPC1 (0.32) NPC1MAPTRAB9ATSHR
SCHEMBL14735686 0.90 RAPGEF3 (0.31) MAPT
Hydrochloric Acid SCHEMBL812125 0.90 NPC1 (0.32) NPC1MAPTRAB9ATSHR
SCHEMBL18142329 0.90
SCHEMBL6047534 0.90 TRPV1 (0.32)
SCHEMBL2803241 0.90 ALDH1A1 (0.31) NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2465879-B1 Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same MITSUI CHEMICALS INC (JP) 2019-04-24 EP disclosed
EP-2511305-A1 Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same Mitsui Chemicals, Inc. (JP) 2012-10-17 EP disclosed
EP-2465878-A1 Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same Mitsui Chemicals, Inc. (JP) 2012-06-20 EP disclosed
EP-2465879-A1 Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same Mitsui Chemicals, Inc. (JP) 2012-06-20 EP disclosed
US-7795194-B2 Synthetic lubricating oil and lubricating oil composition MITSUI CHEMICALS, INC. (JP) 2010-09-14 US disclosed
US-20060116303-A1 decene-ethylene copolymer, zirconium, titanium or hafnium fluorene-containing complexes, organometallics; improved high thermal oxidation stability, viscosity index, low-temperature viscosity properties and shear stability MITSUI CHEMICALS, INC. (JP) 2006-06-01 US disclosed
EP-1548018-A1 CROSSLINKED METALLOCENE COMPOUND FOR OLEFIN POLYMERIZATION AND METHOD OF POLYMERIZING OLEFIN WITH THE SAME Mitsui Chemicals, Inc. (JP) 2005-06-29 EP disclosed