SCHEMBL2869225

SCHEMBL2869225

N#CCc1cc(Cl)c(Cl)c(Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 1/20 0.39
HPGD P15428 3/20 0.36
CYP3A4 P08684 2/20 0.36
HSD17B10 Q99714 2/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
ENPP2 Q13822 1/20 0.35
CSNK2A1 P68400 2/20 0.33
LMNA P02545 2/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
MMP3 P08254 1/20 0.33
AHR P35869 4/20 0.32
CYP2A6 P11509 1/20 0.32
CYP1B1 Q16678 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23578177 0.81 KDM4E (0.39) KDM4ETDP1HPGDENPP2CSNK2A1
SCHEMBL14331562 0.81 KDM4E (0.39) KDM4ETDP1HPGDENPP2CSNK2A1
SCHEMBL3015810 0.81 ALDH1A1 (0.44) KDM4ETDP1ALDH1A1HPGDCYP3A4
SCHEMBL4007007 0.78 KDM4E (0.52) KDM4ETDP1ENPP2CSNK2A1LMNA
SCHEMBL13748018 0.78 KDM4E (0.37) KDM4ETDP1ENPP2CSNK2A1LMNA
SCHEMBL8658364 0.77 KDM4E (0.48) KDM4ETDP1HPGDENPP2CSNK2A1
SCHEMBL502201 0.77 KDM4E (0.48) KDM4ETDP1CYP3A4ENPP2LMNA
SCHEMBL29609180 0.76 IDO1 (0.52) KDM4ETDP1HPGDENPP2LMNA
SCHEMBL2308 0.76 IDO1 (0.52) KDM4ETDP1HPGDENPP2LMNA
SCHEMBL9955613 0.76 KDM4E (0.36) KDM4ETDP1ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102119240-B Surface treating agent for copper or copper alloy and use thereof SHIKOKU CHEM 2014-07-30 CN disclosed
WO-2010016620-A1 SURFACE TREATING AGENT FOR COPPER OR COPPER ALLOY AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2010-02-11 WO disclosed
EP-0679645-A1 Pharmacologically active CNS pyridmidin compounds THE WELLCOME FOUNDATION LIMITED (GB) 1995-11-02 EP disclosed
EP-0459819-A2 Pharmacologically active CNS compound THE WELLCOME FOUNDATION LIMITED (GB) 1991-12-04 EP disclosed