Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28598599 | 0.92 | EGFR (0.44) | EGFR | |
| SCHEMBL4735709 | 0.80 | EGFR (0.37) | EGFR | |
| SCHEMBL29695387 | 0.80 | EGFR (0.52) | EGFR | |
| SCHEMBL2112318 | 0.80 | EGFR (0.52) | EGFR | |
| SCHEMBL16296825 | 0.80 | EGFR (0.42) | EGFR | |
| SCHEMBL22125243 | 0.80 | TAAR1 (0.39) | — | |
| SCHEMBL14406854 | 0.78 | EGFR (0.39) | EGFR | |
| SCHEMBL27192332 | 0.76 | LPL (0.38) | EGFR | |
| SCHEMBL16385172 | 0.76 | EGFR (0.38) | EGFR | |
| SCHEMBL31118339 | 0.75 | EGFR (0.44) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195498-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2021-07-30 | — | — | CN | disclosed |