Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 5/20 | 0.54 |
| ▸ | AURKA | O14965 | 3/20 | 0.52 |
| ▸ | CDK2 | P24941 | 7/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | CHUK | O15111 | 1/20 | 0.48 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29371794 | 1.00 | CAMK2D (0.54) | CAMK2DAURKACDK2GSK3BCDK4 | |
| SCHEMBL28680649 | 0.89 | SYK (0.48) | CAMK2DAURKACDK2KCNH2CCNT1 | |
| SCHEMBL29372471 | 0.89 | SYK (0.48) | CAMK2DAURKACDK2KCNH2CCNT1 | |
| SCHEMBL29005352 | 0.84 | HDAC1 (0.49) | CAMK2DCDK2KCNH2MAPK8MAPK10 | |
| SCHEMBL28672749 | 0.82 | HDAC1 (0.62) | — | |
| SCHEMBL28678979 | 0.78 | CAMK2D (0.51) | CAMK2DAURKACDK2GSK3BCDK4 | |
| SCHEMBL28676599 | 0.78 | CDK2 (0.57) | CDK2GSK3BCDK4IKBKBCHUK | |
| SCHEMBL29368279 | 0.78 | CAMK2D (0.51) | CAMK2DAURKACDK2GSK3BCDK4 | |
| SCHEMBL28697590 | 0.77 | LCK (0.53) | CAMK2DAURKACDK2GSK3BCDK4 | |
| SCHEMBL29371192 | 0.77 | LCK (0.53) | CAMK2DAURKACDK2GSK3BCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999210-B | Group of 2-phenylamino-4-triazolyl pyrimidine derivatives and application thereof | 郑州大学第一附属医院 | 2023-05-23 | — | — | CN | disclosed |
| CN-113999210-A | Group of 2-phenylamino-4-triazolyl pyrimidine derivatives and application thereof | 郑州大学第一附属医院 | 2022-02-01 | — | — | CN | disclosed |