Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | EEF2K | O00418 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28684205 | 0.81 | ALDH1A1 (0.52) | SMN1; SMN2POLBKMT2APKMALDH1A1 | |
| SCHEMBL30309447 | 0.80 | KMT2A (0.61) | SMN1; SMN2POLBKMT2APKMALDH1A1 | |
| SCHEMBL30309498 | 0.78 | ALDH1A1 (0.52) | SMN1; SMN2POLBKMT2APKMALDH1A1 | |
| SCHEMBL22164024 | 0.78 | ALDH1A1 (0.52) | SMN1; SMN2POLBKMT2APKMALDH1A1 | |
| SCHEMBL852655 | 0.76 | ALDH1A1 (0.66) | POLBKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL30309487 | 0.76 | ALDH1A1 (0.66) | POLBKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL17322968 | 0.75 | GAA (0.60) | KMT2AALDH1A1LMNAMEN1GAA | |
| SCHEMBL8462703 | 0.74 | HTT (0.60) | SMN1; SMN2KMT2APKMALDH1A1LMNA | |
| SCHEMBL30725831 | 0.74 | HTT (0.60) | SMN1; SMN2KMT2APKMALDH1A1LMNA | |
| SCHEMBL15687836 | 0.74 | KMT2A (0.51) | SMN1; SMN2POLBKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113880814-B | Pyrimidine amine compound and application thereof | 杭州百诚医药科技股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-113880814-A | Pyrimidinamine compound and application thereof | 杭州百诚医药科技股份有限公司 | 2022-01-04 | — | — | CN | disclosed |