Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | EEF2K | O00418 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17450444 | 0.85 | MAPT (0.50) | ALDH1A1KDM4EHSD17B10EEF2KSMN1; SMN2 | |
| SCHEMBL28694232 | 0.81 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EHSD17B10EEF2KSMN1; SMN2 | |
| SCHEMBL30198967 | 0.77 | CPS1 (0.52) | ALDH1A1KDM4E | |
| SCHEMBL21245769 | 0.77 | CPS1 (0.52) | ALDH1A1KDM4E | |
| SCHEMBL31455427 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HSD17B10L3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL14574181 | 0.76 | CA12 (0.50) | KDM4EEEF2KPKMFAAHPOLB | |
| SCHEMBL30309546 | 0.75 | HSD11B1 (0.51) | ALDH1A1KDM4EHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL22164010 | 0.75 | HSD11B1 (0.51) | ALDH1A1KDM4EHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL11939056 | 0.75 | EEF2K (0.59) | ALDH1A1L3MBTL1EEF2KSMN1; SMN2MAPT | |
| SCHEMBL914192 | 0.72 | HDAC1 (0.57) | ALDH1A1MEN1KMT2AMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113880814-B | Pyrimidine amine compound and application thereof | 杭州百诚医药科技股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-113880814-A | Pyrimidinamine compound and application thereof | 杭州百诚医药科技股份有限公司 | 2022-01-04 | — | — | CN | disclosed |