Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1472705 | 0.88 | SLC7A5 (0.41) | CHRNB2CHRNA4SLC7A5 | |
| SCHEMBL29499452 | 0.88 | SLC7A5 (0.41) | CHRNB2CHRNA4SLC7A5 | |
| SCHEMBL10329129 | 0.84 | CHRNB2 (0.35) | CHRNB2CHRNA4SLC7A5 | |
| SCHEMBL31370973 | 0.80 | CHRNB2 (0.35) | CHRNB2CHRNA4DGAT1MCHR1 | |
| SCHEMBL24617877 | 0.79 | CHRNB2 (0.36) | CHRNB2CHRNA4CYP19A1MCHR1 | |
| SCHEMBL28971358 | 0.78 | TRPV1 (0.32) | CHRNB2CHRNA4 | |
| SCHEMBL2303010 | 0.78 | GRM4 (0.41) | CHRNB2CHRNA4 | |
| SCHEMBL15918726 | 0.77 | CHRNB2 (0.42) | CHRNB2CHRNA4DGAT1MCHR1 | |
| SCHEMBL17099993 | 0.76 | ALDH1A1 (0.41) | CHRNB2CHRNA4 | |
| SCHEMBL29700311 | 0.76 | ALDH1A1 (0.41) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113880755-B | Preparation method of 2-bromo-5- (trifluoromethoxy) pyridine | 成都药明康德新药开发有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-113880755-A | Preparation method of 2-bromo-5- (trifluoromethoxy) pyridine | 成都药明康德新药开发有限公司 | 2022-01-04 | — | — | CN | disclosed |