Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28694487 | 1.00 | MAPT (0.49) | MAPTMAPK1ALDH1A1NPC1HTT | |
| SCHEMBL29467204 | 1.00 | MAPT (0.49) | MAPTMAPK1ALDH1A1NPC1HTT | |
| SCHEMBL29467203 | 1.00 | MAPT (0.49) | MAPTMAPK1ALDH1A1NPC1HTT | |
| SCHEMBL24689326 | 0.89 | MAPT (0.64) | MAPTMAPK1ALDH1A1NPC1HTT | |
| SCHEMBL30461757 | 0.87 | FPR2 (0.47) | MAPTMAPK1ALDH1A1USP30LMNA | |
| SCHEMBL25273382 | 0.87 | FPR2 (0.47) | MAPTMAPK1ALDH1A1USP30LMNA | |
| SCHEMBL22638389 | 0.86 | KMT2A (0.46) | MAPTMAPK1GFERKMT2APLA2G1B | |
| SCHEMBL22638386 | 0.86 | KMT2A (0.46) | MAPTMAPK1GFERKMT2APLA2G1B | |
| SCHEMBL28694478 | 0.85 | MAPT (0.46) | MAPTMAPK1ALDH1A1L3MBTL1USP30 | |
| SCHEMBL28694480 | 0.85 | MAPT (0.46) | MAPTMAPK1ALDH1A1L3MBTL1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114126713-B | Substituted benzimidazolone compounds | 百时美施贵宝公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114126713-A | Substituted benzimidazolone compounds | 百时美施贵宝公司 | 2022-03-01 | — | — | CN | disclosed |