Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 11/20 | 0.62 |
| ▸ | AXL | P30530 | 11/20 | 0.58 |
| ▸ | MERTK | Q12866 | 4/20 | 0.58 |
| ▸ | FLT1 | P17948 | 3/20 | 0.58 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.58 |
| ▸ | KDR | P35968 | 2/20 | 0.58 |
| ▸ | AURKA | O14965 | 1/20 | 0.58 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.58 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | LYN | P07948 | 1/20 | 0.58 |
| ▸ | RET | P07949 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | HCK | P08631 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31105630 | 0.97 | MET (0.67) | METAXLMERTKFLT1AURKB | |
| SCHEMBL372017 | 0.94 | MET (0.66) | METAXLMERTKFLT1AURKB | |
| SCHEMBL29883010 | 0.94 | MET (0.66) | METAXLMERTKFLT1AURKB | |
| SCHEMBL374207 | 0.91 | AXL (0.55) | METAXLMERTKFLT1AURKB | |
| SCHEMBL29453833 | 0.91 | AXL (0.57) | METAXLMERTKFLT1AURKB | |
| SCHEMBL22750248 | 0.91 | AXL (0.57) | METAXLMERTKFLT1AURKB | |
| Pyruvate SCHEMBL29195420 | 0.90 | MET (0.61) | METAXLMERTKFLT1AURKB | |
| SCHEMBL21200899 | 0.90 | AXL (0.58) | METAXLMERTKFLT1AURKB | |
| SCHEMBL21201003 | 0.89 | AXL (0.57) | METAXLMERTKFLT1AURKB | |
| Glutarate SCHEMBL29195414 | 0.88 | MET (0.58) | METAXLMERTKFLT1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924288-B | Quinolinyl-containing compound, pharmaceutical composition and application thereof | 北京普祺医药科技股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-113924288-A | Quinolyl-containing compound, pharmaceutical composition and application thereof | 北京普祺医药科技有限公司 | 2022-01-11 | — | — | CN | disclosed |