Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 8/20 | 0.34 |
| ▸ | MAOA | P21397 | 5/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28707255 | 0.88 | APP (0.40) | APPMAOBMAOA | |
| SCHEMBL28707209 | 0.84 | MAPT (0.43) | HDAC6MAPK1 | |
| SCHEMBL23012913 | 0.77 | APP (0.46) | APPHDAC6MAOBMAOAMAPK1 | |
| SCHEMBL23033594 | 0.75 | ADRA2A (0.48) | HDAC6MAOB | |
| SCHEMBL28710788 | 0.73 | NPC1 (0.36) | HDAC6 | |
| SCHEMBL23012822 | 0.72 | HDAC6 (0.37) | HDAC6 | |
| SCHEMBL23012217 | 0.72 | MAOB (0.57) | MAOBMAOA | |
| SCHEMBL28713901 | 0.71 | MAPT (0.37) | HDAC6MAPK1 | |
| SCHEMBL23012523 | 0.68 | GSK3B (0.45) | — | |
| SCHEMBL29479664 | 0.68 | GSK3B (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |