Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23012822 | 0.89 | HDAC6 (0.37) | MAPTRAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL28935974 | 0.84 | MAPT (0.44) | MAPTRAB9ASMN1; SMN2TP53PTGS2 | |
| SCHEMBL28695261 | 0.84 | APP (0.41) | HDAC6MAPK1 | |
| SCHEMBL28710788 | 0.83 | NPC1 (0.36) | MAPTRAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL28713901 | 0.83 | MAPT (0.37) | MAPTRAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL28701697 | 0.79 | HDAC6 (0.36) | MAPTRAB9ASMN1; SMN2TP53PTGS2 | |
| SCHEMBL23012299 | 0.78 | RAB9A (0.69) | MAPTRAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL23033392 | 0.76 | MAPT (0.50) | MAPTRAB9ASMN1; SMN2TP53PTGS2 | |
| SCHEMBL29479820 | 0.76 | MAPT (0.50) | MAPTRAB9ASMN1; SMN2TP53PTGS2 | |
| SCHEMBL29479691 | 0.76 | HDAC6 (0.54) | MAPTRAB9ASMN1; SMN2TP53PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |