Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 19/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29434532 | 0.92 | GPR84 (0.65) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL25658396 | 0.88 | GPR84 (0.63) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL14327789 | 0.85 | GPR84 (0.65) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL16788630 | 0.84 | GPR84 (0.55) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL21615657 | 0.83 | GPR84 (0.82) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL16788633 | 0.82 | GPR84 (0.62) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL16263334 | 0.81 | GPR84 (0.50) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL16788632 | 0.81 | GPR84 (0.53) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL16788629 | 0.79 | GPR84 (0.49) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL16788631 | 0.79 | GPR84 (0.51) | GPR84MEN1KMT2AKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114026095-A | Alternative process for the preparation of 4-phenyl-5-alkoxycarbonyl-2-thiazol-2-yl-1, 4-dihydropyrimidin-6-yl ] methyl ] -3-oxo-5, 6,8,8 a-tetrahydro-1H-imidazo [1,5-a ] pyrazin-2-yl ] -carboxylic acid | 豪夫迈·罗氏有限公司 | 2022-02-08 | — | — | CN | claimed |
| CN-115697971-A | Cyclobutyldihydroquinoline sulfonamide compound | 美国安进公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-114026095-A | Alternative process for the preparation of 4-phenyl-5-alkoxycarbonyl-2-thiazol-2-yl-1, 4-dihydropyrimidin-6-yl ] methyl ] -3-oxo-5, 6,8,8 a-tetrahydro-1H-imidazo [1,5-a ] pyrazin-2-yl ] -carboxylic acid | 豪夫迈·罗氏有限公司 | 2022-02-08 | — | — | CN | disclosed |