Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 19/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25658396 | 0.95 | GPR84 (0.63) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL28695345 | 0.92 | GPR84 (0.58) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL14327789 | 0.92 | GPR84 (0.65) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL16788630 | 0.91 | GPR84 (0.55) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL16788633 | 0.89 | GPR84 (0.62) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL16263334 | 0.88 | GPR84 (0.50) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL16788632 | 0.88 | GPR84 (0.53) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL16788629 | 0.86 | GPR84 (0.49) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL16788631 | 0.86 | GPR84 (0.51) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL14424202 | 0.84 | GPR84 (0.47) | GPR84MEN1KMT2AKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119735588-A | Cyclobutyl dihydroquinolines sulfonamide compounds | 美国安进公司 | 2025-04-01 | — | — | CN | claimed |
| WO-2024130425-A1 | METHODS OF MAKING 2-AMINO-L-(3-HYDROXY-2,6-DIMETHYLPHENYL)-5,6- DIMETHYL-LH-PYRROLO-[2,3-B]PYRIDINE-3-CARBOXAMIDE, A MYTL INHIBITOR | REPARE THERAPEUTICS INC. (CA) | 2024-06-27 | — | — | WO | claimed |
| US-20230234948-A1 | CYCLOPROPYL DIHYDROQUINOLINE SULFONAMIDE COMPOUNDS | AMGEN INC. (US) | 2023-07-27 | — | — | US | claimed |
| EP-4164748-A1 | CYCLOPROPYL DIHYDROQUINOLINE SULFONAMIDE COMPOUNDS | Amgen Inc. (US) | 2023-04-19 | — | — | EP | claimed |
| EP-4165024-A1 | CYCLOBUTYL DIHYDROQUINOLINE SULFONAMIDE COMPOUNDS | Amgen Inc. (US) | 2023-04-19 | — | — | EP | claimed |
| CN-115697971-A | Cyclobutyldihydroquinoline sulfonamide compound | 美国安进公司 | 2023-02-03 | — | — | CN | claimed |
| US-20220315588-A1 | ALTERNATIVE PROCESS FOR THE PREPARATION OF 4-PHENYL-5-ALKOXYCARBONYL-2-THIAZOL-2-YL-1,4-DIHYDROPYRIMIDIN-6-YL]METHYL]-3-OXO-5,6,8,8A-TETRAHYDRO-1H-IMIDAZO[1,5-A]PYRAZIN-2-YL]-CARBOXYLIC ACID | HOFFMANN-LA ROCHE INC. (US) | 2022-10-06 | — | — | US | claimed |
| CN-115010565-A | Synthesis method of spiro chiral indolinone containing indole skeleton | 中国科学院大连化学物理研究所 | 2022-09-06 | — | — | CN | claimed |
| EP-3980419-A1 | ALTERNATIVE PROCESS FOR THE PREPARATION OF 4-PHENYL-5-ALKOXYCARBONYL-2-THIAZOL-2-YL-1,4-DIHYDROPYRIMIDIN-6-YL]METHYL]-3-OXO-5,6,8,8A-TETRAHYDRO-1H-IMIDAZO[1,5-A]PYRAZIN-2-YL]-CARBOXYLIC ACID | F. Hoffmann-La Roche AG (CH) | 2022-04-13 | — | — | EP | claimed |
| US-20260102387-A1 | IMMUNOSUPPRESSIVE COMPOUNDS | UNIV BASEL (CH) | 2026-04-16 | — | — | US | disclosed |
| EP-4719603-A1 | SPIROCYCLIC ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER | Boehringer Ingelheim International GmbH (DE) | 2026-04-08 | — | — | EP | disclosed |
| US-20260083723-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR AMYOTROPHIC LATERAL SCLEROSIS | TORAY INDUSTRIES, INC. (JP) | 2026-03-26 | — | — | US | disclosed |
| EP-4706654-A2 | CYCLOPROPYL DIHYDROQUINOLINE SULFONAMIDE COMPOUNDS | Amgen Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| US-12570639-B2 | Tetrahydroquinoline derivative and medicinal use thereof | TORAY INDUSTRIES, INC. (JP) | 2026-03-10 | — | — | US | disclosed |
| US-20220306604-A1 | CYCLOBUTYL DIHYDROQUINOLINE SULFONAMIDE COMPOUNDS | AMGEN INC. (US) | 2022-09-29 | — | — | US | disclosed |
| CN-115010565-A | Synthesis method of spiro chiral indolinone containing indole skeleton | 中国科学院大连化学物理研究所 | 2022-09-06 | — | — | CN | disclosed |
| WO-2022138888-A1 | TETRAHYDROQUINOLINE DERIVATIVE AND MEDICINAL USE THEREOF | 東レ株式会社 | 2022-06-30 | — | — | WO | disclosed |
| CN-111995497-B | Preparation method of allyl alcohol | 苏州大学 | 2022-04-26 | — | — | CN | disclosed |
| EP-3980419-A1 | ALTERNATIVE PROCESS FOR THE PREPARATION OF 4-PHENYL-5-ALKOXYCARBONYL-2-THIAZOL-2-YL-1,4-DIHYDROPYRIMIDIN-6-YL]METHYL]-3-OXO-5,6,8,8A-TETRAHYDRO-1H-IMIDAZO[1,5-A]PYRAZIN-2-YL]-CARBOXYLIC ACID | F. Hoffmann-La Roche AG (CH) | 2022-04-13 | — | — | EP | disclosed |
| WO-2022061271-A1 | ISOMERIZATION OF CYCLOHEXENEDICARBOXYLIC ACID AND ITS DERIVATIVES | IOWA STATE UNIVERSITY RESEARCHFOUNDATION, INC. (US) | 2022-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260083723-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR AMYOTROPHIC LATERAL SCLEROSIS | AIFM2, GPX1, SOD1 | GPR84 3593/4885MEN1 4123/4885KMT2A 2771/4885 |
| US-20220315588-A1 | ALTERNATIVE PROCESS FOR THE PREPARATION OF 4-PHENYL-5-ALKOXYCARBONYL-2-THIAZOL-2-YL-1,4-DIHYDROPYRIMIDIN-6-YL]METHYL]-3-OXO-5,6,8,8A-TETRAHYDRO-1H-IMIDAZO[1,5-A]PYRAZIN-2-YL]-CARBOXYLIC ACID | ZC3HAV1L, ZC3HAV1, XDH | GPR84 3094/4885MEN1 2503/4885KMT2A 1764/4885 |
| US-12570639-B2 | Tetrahydroquinoline derivative and medicinal use thereof | AIFM2, GPX1, GPX4 | GPR84 1459/4885MEN1 1243/4885KMT2A 1522/4885 |
| US-20230234948-A1 | CYCLOPROPYL DIHYDROQUINOLINE SULFONAMIDE COMPOUNDS | TRPV1, SCN7A, TRPA1 | GPR84 844/4885MEN1 3405/4885KMT2A 3483/4885 |
| US-20220306604-A1 | CYCLOBUTYL DIHYDROQUINOLINE SULFONAMIDE COMPOUNDS | TRPV1, SCN7A, TRPA1 | GPR84 688/4885MEN1 3375/4885KMT2A 3248/4885 |
| US-20260102387-A1 | IMMUNOSUPPRESSIVE COMPOUNDS | CHP1, BRD3, IRF3 | GPR84 3676/4885MEN1 2415/4885KMT2A 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.