Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | DTYMK | P23919 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25688674 | 0.86 | POLB (0.47) | POLBOPRD1OPRK1GPR119DTYMK | |
| SCHEMBL28722028 | 0.81 | POLB (0.41) | POLBOPRD1OPRK1GPR119NAMPT | |
| SCHEMBL29760898 | 0.80 | GPR119 (0.47) | POLBOPRD1OPRK1GPR119NAMPT | |
| SCHEMBL23500638 | 0.80 | GPR119 (0.47) | POLBOPRD1OPRK1GPR119NAMPT | |
| SCHEMBL28680198 | 0.80 | GPR119 (0.41) | POLBOPRD1OPRK1GPR119KDM1A | |
| SCHEMBL21856239 | 0.79 | POLB (0.69) | POLBOPRD1OPRK1GPR119DTYMK | |
| SCHEMBL22499445 | 0.77 | POLB (0.57) | POLBOPRD1OPRK1GPR119DTYMK | |
| SCHEMBL21856177 | 0.77 | POLB (0.57) | POLBOPRD1OPRK1GPR119DTYMK | |
| SCHEMBL29506059 | 0.77 | POLB (0.57) | POLBOPRD1OPRK1GPR119DTYMK | |
| SCHEMBL18921641 | 0.76 | GPR119 (0.53) | OPRD1OPRK1GPR119NAMPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874363-B | Protein tyrosine phosphatase inhibitors | ARRAY生物制药公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-114341124-B | Protein tyrosine phosphatase inhibitors | ARRAY生物制药公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-114341124-A | Protein tyrosine phosphatase inhibitors | ARRAY生物制药公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114008035-A | SHP2 phosphatase allosteric inhibitor | 北京盛诺基医药科技股份有限公司 | 2022-02-01 | — | — | CN | disclosed |