Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1350237 | 0.82 | KCNH2 (0.45) | KMT2ATP53PPARGLMNAALDH1A1 | |
| SCHEMBL12629967 | 0.78 | LMNA (0.43) | GUSBKMT2AMAPTALOX15MEN1 | |
| SCHEMBL11742542 | 0.76 | MEN1 (0.45) | KMT2AMAPTALOX15MEN1HPGD | |
| SCHEMBL1349518 | 0.75 | CES2 (0.46) | KCNH2NPC1RAB9AMDM2 | |
| SCHEMBL22009885 | 0.75 | SMN1; SMN2 (0.38) | MAPTHPGDPPARGLMNASMN1; SMN2 | |
| SCHEMBL29396169 | 0.75 | SMN1; SMN2 (0.38) | MAPTHPGDPPARGLMNASMN1; SMN2 | |
| SCHEMBL11306853 | 0.72 | MEN1 (0.54) | GUSBKMT2AMAPTALOX15MEN1 | |
| SCHEMBL182606 | 0.71 | KMT2A (0.41) | KMT2APPARGLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL22852398 | 0.70 | KCNH2 (0.45) | KMT2ATP53PPARGLMNAALDH1A1 | |
| SCHEMBL1347797 | 0.69 | MDM2 (0.40) | PPARGKCNH2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874019-A | Combinations comprising benzodioxoles as GLP-1R agonists for the treatment of NASH/NAFLD and related diseases | 辉瑞大药厂 | 2021-12-31 | — | — | CN | disclosed |