Bromide

Bromide

SCHEMBL28696489

CCC[N+](CC)(CC)Cc1ccccc1.[Br-]

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 1/20 0.44
DNM1 Q05193 2/20 0.52
CHRNA7 P36544 6/20 0.51
CHRNB4 P30926 5/20 0.51
CHRNA3 P32297 5/20 0.51
CYP1A2 P05177 1/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
TP53 P04637 2/20 0.47
MAPK1 P28482 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HTT P42858 2/20 0.46
BCHE P06276 1/20 0.44
CHRNB2 P17787 3/20 0.42
CHRNA4 P43681 3/20 0.42
NPSR1 Q6W5P4 1/20 0.41
SIGMAR1 Q99720 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL25283625 0.98 CHRNA7 (0.50) DNM1CHRNA7CHRNB4CHRNA3CYP1A2
SCHEMBL5944476 0.98 DNM1 (0.50) DNM1CHRNA7CHRNB4CHRNA3CYP1A2
Hydrochloric Acid SCHEMBL8530459 0.96 KDM4E (0.52) DNM1CHRNA7CHRNB4CHRNA3CYP1A2
SCHEMBL8568870 0.96 CYP1A2 (0.49) DNM1CHRNA7CHRNB4CHRNA3CYP1A2
Water SCHEMBL8529210 0.96 CYP1A2 (0.49) DNM1CHRNA7CHRNB4CHRNA3CYP1A2
SCHEMBL19244149 0.96 CHRNA7 (0.50) DNM1CHRNA7CHRNB4CHRNA3CYP1A2
SCHEMBL7630847 0.94 CYP1A2 (0.47) DNM1CHRNA7CHRNB4CHRNA3CYP1A2
Hydrochloric Acid SCHEMBL8530474 0.94 MEN1 (0.50) DNM1CHRNA7CHRNB4CHRNA3CYP1A2
Water SCHEMBL8530421 0.94 CYP1A2 (0.47) DNM1CHRNA7CHRNB4CHRNA3CYP1A2
Bromide SCHEMBL5091817 0.93 DNM1 (0.53) DNM1CHRNA7CHRNB4CHRNA3CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110240681-B Composite demulsifier, composition and application thereof 中国石油化工股份有限公司 2022-03-11 CN disclosed