Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8530474 | 0.98 | MEN1 (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL5944476 | 0.98 | DNM1 (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10614085 | 0.96 | MEN1 (0.49) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Bromide SCHEMBL28696489 | 0.96 | DNM1 (0.52) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8568870 | 0.96 | CYP1A2 (0.49) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Water SCHEMBL8529210 | 0.96 | CYP1A2 (0.49) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL19244149 | 0.96 | CHRNA7 (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Bromide SCHEMBL25283625 | 0.94 | CHRNA7 (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL7630847 | 0.94 | CYP1A2 (0.47) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Water SCHEMBL8530421 | 0.94 | CYP1A2 (0.47) | KDM4EALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117769588-B | Methods and reagents for enhancing chemiluminescent signals | 欧蒙医学实验诊断股份公司 | 2025-02-21 | — | — | CN | claimed |
| CN-117769588-A | Methods and reagents for enhancing chemiluminescent signals | 欧蒙医学实验诊断股份公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117769588-B | Methods and reagents for enhancing chemiluminescent signals | 欧蒙医学实验诊断股份公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-117769588-A | Methods and reagents for enhancing chemiluminescent signals | 欧蒙医学实验诊断股份公司 | 2024-03-26 | — | — | CN | disclosed |
| US-20160122450-A1 | SYNTHESIS OF A SUBSTITUTED FURAN | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-05-05 | — | — | US | disclosed |
| EP-0609455-B1 | PROCESS FOR PRODUCING CRESOLS | SUMITOMO CHEMICAL CO (JP) | 1998-03-11 | — | — | EP | disclosed |
| US-5600026-A | PREVENTING THE FORMATION OF FORMALDEHYDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-04 | — | — | US | disclosed |
| EP-0609455-A1 | PROCESS FOR PRODUCING CRESOLS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-08-10 | — | — | EP | disclosed |
| US-5166451-A | Peroxide mixture and quaternary ammonium salt for reducing the content of primary hydroperoxides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0003835-B1 | A HYDROXY-UREA, PROCESS FOR PRODUCING THE SAME AND A PROCESS FOR PRODUCING A PHENYL-SUBSTITUTED N-METHOXY-N-METHYL-UREA | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-03-02 | — | — | EP | disclosed |
| US-4328166-A | Production of substituted phenylurea | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |
| US-4263219-A | METHYLATION IN TWO-PHASE REACTION MEDIUM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-04-21 | — | — | US | disclosed |
| US-4172782-A | ORGANIC QUATERNARY AMMONIUM SALT USED IN ALKULATION OF BENZYLNITRILE WITH AN ORGANIC HALIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122450-A1 | SYNTHESIS OF A SUBSTITUTED FURAN | DCXR, PFAS, FUT6 | ACHE 1793/4885KDM4E 1069/4885ALDH1A1 516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.