SCHEMBL28697113

SCHEMBL28697113

Cc1ccc(S(=O)(=O)NNC=O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.58
KDM4E B2RXH2 3/20 0.58
HPGD P15428 3/20 0.58
TDP1 Q9NUW8 3/20 0.58
CYP2C9 P11712 3/20 0.58
CYP2C19 P33261 3/20 0.58
CYP3A4 P08684 3/20 0.58
CYP1A2 P05177 2/20 0.58
CYP2D6 P10635 2/20 0.58
ALOX12 P18054 2/20 0.58
MAPT P10636 1/20 0.58
PKM P14618 1/20 0.58
APOBEC3G Q9HC16 1/20 0.58
LMNA P02545 1/20 0.56
POLB P06746 1/20 0.56
GAA P10253 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
MMP1 P03956 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27914683 0.89 ALDH1A1 (0.55) ALDH1A1KDM4EHPGDTDP1CYP2C9
SCHEMBL7627224 0.83 ALDH1A1 (0.72) ALDH1A1KDM4EHPGDTDP1CYP2C9
SCHEMBL11697966 0.79 BCAT1 (0.50) ALDH1A1KDM4EHPGDTDP1CYP2C9
SCHEMBL17764 0.79 GAA (0.59) ALDH1A1KDM4EHPGDTDP1CYP2C9
SCHEMBL29658990 0.79 ALDH1A1 (0.67) ALDH1A1KDM4EHPGDTDP1CYP2C9
SCHEMBL29614846 0.79 ALDH1A1 (0.67) ALDH1A1KDM4EHPGDTDP1CYP2C9
SCHEMBL418582 0.77 GAA (0.68) ALDH1A1KDM4EHPGDTDP1CYP2C9
SCHEMBL16509308 0.76 GAA (0.67) ALDH1A1KDM4EHPGDTDP1CYP2C9
SCHEMBL4021554 0.75 ALDH1A1 (0.72) ALDH1A1KDM4EHPGDTDP1CYP2C9
SCHEMBL28123632 0.75 CA1 (0.63) ALDH1A1KDM4EHPGDTDP1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114409713-A N-unsubstituted ferrocenopyridone derivative and synthesis method thereof 山东师范大学 2022-04-29 CN claimed
CN-113896663-A Heat-sensitive acid generator and preparation method and application thereof 北京印刷学院 2022-01-07 CN disclosed