SCHEMBL28697163

SCHEMBL28697163

Nc1ccc(OC=S)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
TDP1 Q9NUW8 6/20 0.50
CYP3A4 P08684 3/20 0.50
TSHR P16473 2/20 0.50
MAPK1 P28482 2/20 0.46
MAOA P21397 3/20 0.42
MAPT P10636 6/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
MAOB P27338 2/20 0.41
TEAD4 Q15561 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.39
GAA P10253 2/20 0.39
POLB P06746 1/20 0.39
MITF O75030 1/20 0.39
GFER P55789 1/20 0.39
NLRP1 Q9C000 1/20 0.39
NOD2 Q9HC29 1/20 0.39
RAB9A P51151 2/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6574765 0.78 RELA (0.33) ALDH1A1TDP1CYP3A4TSHRMEN1
SCHEMBL2624868 0.74 ALDH1A1 (0.50) ALDH1A1TDP1CYP3A4TSHRMAPK1
SCHEMBL2494427 0.74
SCHEMBL715942 0.74 ALDH1A1 (0.50) ALDH1A1TDP1CYP3A4TSHRMAPK1
SCHEMBL11115657 0.74 CA1 (0.58) ALDH1A1TDP1CYP3A4TSHRMAPK1
SCHEMBL7867836 0.74 IDO1 (0.33)
SCHEMBL5828142 0.74
SCHEMBL6570976 0.74 CYP2A6 (0.42) ALDH1A1MAPK1MAOAMAPTMEN1
SCHEMBL13665389 0.74 ALDH1A1 (0.57) ALDH1A1TDP1CYP3A4TSHRMAPK1
SCHEMBL4460171 0.74 MEN1 (0.50) ALDH1A1TDP1CYP3A4MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113929695-B Sulfimide psoralen derivatives, and preparation method and application thereof 南开大学 2024-06-07 CN claimed
CN-117486662-A Method for synthesizing sulfoxide compound by heterogeneous catalysis 成都理工大学 2024-02-02 CN claimed
CN-122010800-A A kind of substituted thiophenol is a process for the selective alkylation of 大连理工大学 2026-05-12 CN disclosed
CN-113929695-B Sulfimide psoralen derivatives, and preparation method and application thereof 南开大学 2024-06-07 CN disclosed
CN-117486662-A Method for synthesizing sulfoxide compound by heterogeneous catalysis 成都理工大学 2024-02-02 CN disclosed
CN-113651734-B Method for catalytically oxidizing thioether into sulfone 成都理工大学 2023-02-14 CN disclosed
CN-113929695-A Sulfenimide psoralen derivatives, and preparation method and application thereof 南开大学 2022-01-14 CN disclosed