Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28935351 | 0.98 | MEN1 (0.40) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL27692685 | 0.92 | KMT2A (0.37) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL2851915 | 0.92 | KMT2A (0.37) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL28697224 | 0.90 | MEN1 (0.46) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL11617419 | 0.89 | MEN1 (0.39) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL23859895 | 0.88 | MEN1 (0.47) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL7106303 | 0.88 | MEN1 (0.47) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL28935350 | 0.88 | MEN1 (0.43) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL25173893 | 0.88 | MEN1 (0.47) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL486917 | 0.88 | MEN1 (0.47) | MEN1KMT2AMAPTATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174263-A | Non-lysosomal glucosylceramidase inhibitors and uses thereof | 阿勒克图治疗公司 | 2022-03-11 | — | — | CN | disclosed |