Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5405317 | 0.87 | SLC6A4 (0.59) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL4648603 | 0.83 | SLC6A4 (0.56) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL5400233 | 0.83 | SLC6A4 (0.56) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL28228539 | 0.82 | BACE1 (0.54) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| Methyl Alcohol SCHEMBL10694365 | 0.82 | SLC6A4 (0.58) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL3673985 | 0.82 | BACE1 (0.54) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| Naphthalene SCHEMBL9359039 | 0.82 | BACE1 (0.54) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL25339334 | 0.78 | SLC6A4 (0.51) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL4458583 | 0.78 | SLC6A4 (0.55) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL4671471 | 0.78 | SLC6A4 (0.51) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952300-B | 5-or 8-substituted imidazo [1,5-a ] pyridines | 百济神州有限公司 | 2022-01-18 | — | — | CN | disclosed |