Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 19/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28680477 | 0.88 | MCL1 (0.57) | MCL1 | |
| SCHEMBL28673390 | 0.87 | MCL1 (0.65) | MCL1 | |
| SCHEMBL28681436 | 0.85 | STAT3 (0.61) | MCL1CACNA1BAPBA1 | |
| SCHEMBL28696167 | 0.83 | MCL1 (0.55) | MCL1CACNA1BAPBA1 | |
| SCHEMBL28695985 | 0.82 | STAT3 (0.55) | MCL1CACNA1BAPBA1 | |
| SCHEMBL28699068 | 0.81 | STAT3 (0.54) | MCL1CACNA1BAPBA1 | |
| SCHEMBL28673399 | 0.81 | MEN1 (0.58) | MCL1CACNA1BAPBA1 | |
| SCHEMBL28683183 | 0.81 | CHEK1 (0.58) | MCL1CACNA1BAPBA1 | |
| SCHEMBL28672796 | 0.81 | MCL1 (0.46) | MCL1CACNA1BAPBA1 | |
| SCHEMBL1899741 | 0.80 | STAT3 (0.73) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113747920-A | Immune checkpoint inhibitor combination therapy using quinoline carboxamide derivatives | 株式会社益力多本社 | 2021-12-03 | — | — | CN | disclosed |
| CN-112703001-A | Combination cancer therapy using quinoline carboxamide derivatives | 株式会社益力多本社 | 2021-04-23 | — | — | CN | disclosed |