SCHEMBL28698317

SCHEMBL28698317

CC(Br)CCCO[Si](C)(C)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31087543 0.92 DUT (0.34) DUT
SCHEMBL25461568 0.88 DUT (0.31) DUT
SCHEMBL14928560 0.81 DUT (0.34) DUT
SCHEMBL3605071 0.80 DUT (0.36) DUT
SCHEMBL31644722 0.80 DUT (0.36) DUT
SCHEMBL6393715 0.80 DUT (0.36) DUT
SCHEMBL18088167 0.78 DUT (0.35) DUT
SCHEMBL28538333 0.78 DUT (0.43) DUT
SCHEMBL8063404 0.78 DUT (0.43) DUT
SCHEMBL12096026 0.78 DUT (0.36) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114057770-B Bifunctional compounds targeting EGFR protein degradation 成都先导药物开发股份有限公司 2023-05-02 CN disclosed
CN-114057770-A Bifunctional compounds targeting EGFR protein degradation 成都先导药物开发股份有限公司 2022-02-18 CN disclosed