SCHEMBL3605071

SCHEMBL3605071

CC(O)CCCO[Si](C)(C)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.36
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31644722 1.00 DUT (0.36) DUTMAPK1
SCHEMBL6393715 1.00 DUT (0.36) DUTMAPK1
SCHEMBL31644643 0.94 DUT (0.35) DUTMAPK1
SCHEMBL31644831 0.94 DUT (0.35) DUTMAPK1
SCHEMBL3206063 0.94 DUT (0.35) DUTMAPK1
SCHEMBL6379670 0.92 DUT (0.34) DUT
SCHEMBL11292040 0.92 DUT (0.34) DUT
SCHEMBL15902883 0.92 DUT (0.34) DUT
SCHEMBL1313907 0.88 MAPK1 (0.33) DUTMAPK1
SCHEMBL1313910 0.88 MAPK1 (0.33) DUTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213493-A1 NANOMATERIALS COMPRISING TRIOLS BEAM THERAPEUTICS INC. 2025-07-03 US disclosed
US-12296053-B2 Nanomaterials comprising triols BEAM THERAPEUTICS INC. (US) 2025-05-13 US disclosed
EP-4540222-A1 NANOMATERIALS COMPRISING TRIOLS Beam Therapeutics Inc. (US) 2025-04-23 EP disclosed
CN-119698406-A Nanomaterials comprising triols 比姆医疗股份有限公司 2025-03-25 CN disclosed
US-20240252443-A1 NANOMATERIALS COMPRISING TRIOLS BEAM THERAPEUTICS INC. 2024-08-01 US disclosed
WO-2024019936-A1 NANOMATERIALS COMPRISING TRIOLS BEAM THERAPEUTICS INC. (US) 2024-01-25 WO disclosed
EP-3763367-A1 PYRIDINE-PYRAZOLE DERIVATIVES AS HISTONE DEMETHYLASE INHIBITORS Celgene Quanticel Research, Inc. (US) 2021-01-13 EP disclosed
EP-2928471-B1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RES INC (US) 2020-10-14 EP disclosed
US-10173996-B2 Histone demethylase inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2019-01-08 US disclosed
US-9714230-B2 Histone demethylase inhibitors Celgene Quantical Research, Inc. (US) 2017-07-25 US disclosed
US-20060287309-A1 [1,8]NAPHTHYRIDIN-2-ONES AND RELATED COMPOUNDS FOR THE TREATMENT OF SCHIZOPHRENIA WARNER-LAMBERT COMPANY LLC 2006-12-21 US disclosed
US-20060167053-A1 Heteroarylcarbamoylbenzene derivative MSD K.K. (JP) 2006-07-27 US disclosed
EP-1660497-A1 [ 1,8]NAPHTHYRIDIN-2-ONES AND RELATED COMPOUNDS FOR THE TREATMENT OF SCHIZOPHRENIA Warner-Lambert Company LLC (US) 2006-05-31 EP disclosed
WO-2006035301-A2 ERYTHROMYCIN A DERIVATIVES AS ANTIBACTERIAL AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-04-06 WO disclosed
EP-1600442-A1 HETEROARYLCARBAMOYLBENZENE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-11-30 EP disclosed
US-6967196-B1 Sulfonamide compounds and uses thereof BRISTOL-MYERS SQUIBB COMPANY (US) 2005-11-22 US disclosed
WO-2005019215-A1 [1,8]NAPHTHYRIDIN-2-ONES AND RELATED COMPOUNDS FOR THE TREATMENT OF SCHIZOPHRENIA WARNER-LAMBERT COMPANY LLC (US) 2005-03-03 WO disclosed
US-20050043309-A1 [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia WARNER-LAMBERT COMPANY LLC 2005-02-24 US disclosed
EP-1159263-A1 NOVEL SULFONAMIDE COMPOUNDS AND USES THEREOF Merck & Co., Inc. (US) 2001-12-05 EP disclosed
WO-2000050391-A1 NOVEL SULFONAMIDE COMPOUNDS AND USES THEREOF MERCK & CO., INC. (US) 2000-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10173996-B2 Histone demethylase inhibitors KDM1B, KDM5A, KDM1A DUT 205/4885MAPK1 2685/4885
US-20240252443-A1 NANOMATERIALS COMPRISING TRIOLS PNPLA2, LIPA, PHOSPHO1 DUT 1885/4885MAPK1 4328/4885
US-20050043309-A1 [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia DRD1, DRD2, DRD3 DUT 1865/4885MAPK1 1810/4885
US-12296053-B2 Nanomaterials comprising triols PNPLA2, LIPA, PHOSPHO1 DUT 1885/4885MAPK1 4328/4885
US-20060287309-A1 [1,8]NAPHTHYRIDIN-2-ONES AND RELATED COMPOUNDS FOR THE TREATMENT OF SCHIZOPHRENIA DRD1, DRD2, DRD3 DUT 1865/4885MAPK1 1810/4885
US-20060167053-A1 Heteroarylcarbamoylbenzene derivative GCK, GCKR, GALK1 DUT 1768/4885MAPK1 1086/4885
US-20250213493-A1 NANOMATERIALS COMPRISING TRIOLS PNPLA2, LIPA, PHOSPHO1 DUT 1885/4885MAPK1 4328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.