Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27693159 | 0.79 | MAPK1 (0.46) | MAPK1ALDH1A1L3MBTL1CYP19A1PAM | |
| SCHEMBL11035695 | 0.76 | CYP19A1 (0.47) | MAPK1ALDH1A1L3MBTL1CYP19A1TSHR | |
| SCHEMBL27942071 | 0.73 | MAPK1 (0.50) | MAPK1ALDH1A1L3MBTL1CYP19A1PAM | |
| SCHEMBL14833338 | 0.72 | CYP19A1 (0.47) | ALDH1A1L3MBTL1CYP19A1KMT2ACES2 | |
| SCHEMBL17315100 | 0.72 | CYP19A1 (0.46) | MAPK1ALDH1A1L3MBTL1CYP19A1PAM | |
| SCHEMBL28457553 | 0.69 | CYP19A1 (0.38) | MAPK1CYP19A1SMN1; SMN2KDM4ECYP1A1 | |
| SCHEMBL17825839 | 0.69 | MEN1 (0.49) | ALDH1A1L3MBTL1CYP19A1KMT2AHPGD | |
| SCHEMBL27738415 | 0.68 | MAPK1 (0.61) | MAPK1ALDH1A1L3MBTL1CYP19A1PAM | |
| SCHEMBL248113 | 0.67 | ALDH1A1 (0.65) | MAPK1ALDH1A1L3MBTL1CYP19A1PAM | |
| SCHEMBL664857 | 0.67 | ALDH1A1 (0.65) | MAPK1ALDH1A1L3MBTL1CYP19A1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952297-B | Compound (I) | 奥斯陆大学 | 2022-02-25 | — | — | CN | disclosed |