Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259259 | 0.81 | MEN1 (0.51) | MEN1KMT2AL3MBTL1HDAC8HDAC6 | |
| SCHEMBL3936139 | 0.74 | MEN1 (0.48) | MEN1KMT2AL3MBTL1HDAC8HDAC6 | |
| SCHEMBL14833338 | 0.72 | CYP19A1 (0.47) | MEN1KMT2AL3MBTL1HDAC8HDAC6 | |
| SCHEMBL7468100 | 0.71 | CYP19A1 (0.50) | MEN1KMT2AALDH1A1MAPTCYP19A1 | |
| SCHEMBL7107935 | 0.71 | ALDH1A1 (0.77) | MEN1KMT2AL3MBTL1HDAC8HDAC6 | |
| SCHEMBL9563921 | 0.70 | ALDH1A1 (0.75) | MEN1KMT2AL3MBTL1HDAC8HDAC6 | |
| SCHEMBL29185687 | 0.70 | MEN1 (0.50) | MEN1KMT2AL3MBTL1HDAC8HDAC6 | |
| SCHEMBL28698664 | 0.69 | MAPK1 (0.45) | KMT2AL3MBTL1ALDH1A1CYP19A1SMN1; SMN2 | |
| SCHEMBL4338282 | 0.69 | KDM4E (0.50) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL6470572 | 0.68 | MEN1 (0.65) | MEN1KMT2AHDAC8HDAC6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113387894-B | 1-N-benzene acetonitrile amido-triazole and pyrimidine derivative, preparation method and application thereof | 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) | 2023-02-24 | — | — | CN | claimed |
| CN-113387894-A | 1-N-benzene acetonitrile amido-triazole and pyrimidine derivative, preparation method and application thereof | 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) | 2021-09-14 | — | — | CN | claimed |
| CN-113387894-B | 1-N-benzene acetonitrile amido-triazole and pyrimidine derivative, preparation method and application thereof | 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) | 2023-02-24 | — | — | CN | disclosed |
| CN-113387894-A | 1-N-benzene acetonitrile amido-triazole and pyrimidine derivative, preparation method and application thereof | 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) | 2021-09-14 | — | — | CN | disclosed |
| EP-3229801-A1 | FACTOR IXA INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016094260-A1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-06-16 | — | — | WO | disclosed |