Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870939 | 0.82 | TDP1 (0.48) | TDP1POLBKMT2ANPC1RAB9A | |
| Ethylene SCHEMBL28282927 | 0.73 | TDP1 (0.56) | TDP1POLBKMT2AMEN1HSD17B10 | |
| Ethylene SCHEMBL15068230 | 0.73 | TDP1 (0.56) | TDP1POLBKMT2AMEN1HSD17B10 | |
| SCHEMBL27925985 | 0.73 | ALDH1A1 (0.54) | TDP1POLBKMT2ANPC1RAB9A | |
| SCHEMBL15095081 | 0.73 | HDAC4 (0.50) | TDP1POLBKMT2ANPC1RAB9A | |
| SCHEMBL38726 | 0.73 | TDP1 (0.61) | TDP1POLBKMT2AMEN1HSD17B10 | |
| SCHEMBL11904537 | 0.73 | TDP1 (0.61) | TDP1POLBKMT2AMEN1HSD17B10 | |
| SCHEMBL23270946 | 0.73 | KMT2A (0.50) | TDP1POLBKMT2ANPC1RAB9A | |
| SCHEMBL28673640 | 0.72 | HDAC4 (0.40) | TDP1POLBKMT2ANPC1RAB9A | |
| Ethylene Glycol SCHEMBL28237462 | 0.71 | POLB (0.48) | TDP1POLBKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113845499-A | Method for synthesizing 2, 5-furandicarboxylic acid by using N-heterocyclic carbene to catalyze carbon dioxide | 南京先进生物材料与过程装备研究院有限公司 | 2021-12-28 | — | — | CN | disclosed |