SCHEMBL28699114

SCHEMBL28699114

C[C@]1(CCOP(=O)(O)O)CO1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 8/20 0.39
LPAR2 Q9HBW0 6/20 0.39
LPAR1 Q92633 4/20 0.39
CDC25A P30304 2/20 0.34
CDC25B P30305 2/20 0.34
BTN3A1 O00481 1/20 0.32
PGD P52209 1/20 0.31
FBP1 P09467 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2034053 0.85 BTN3A1 (0.50) BTN3A1
SCHEMBL4946200 0.83 BTN3A1 (0.40) BTN3A1
SCHEMBL2978878 0.83 BTN3A1 (0.33) BTN3A1
SCHEMBL2034253 0.83 BTN3A1 (0.47) BTN3A1
SCHEMBL4946206 0.81 BTN3A1 (0.39) BTN3A1
SCHEMBL2978877 0.79 BTN3A1 (0.37) BTN3A1
SCHEMBL2996800 0.75 BTN3A1 (0.47) LPAR3LPAR2LPAR1BTN3A1
SCHEMBL3005883 0.74 BTN3A1 (0.46) LPAR3LPAR2LPAR1BTN3A1
SCHEMBL2995236 0.73 BTN3A1 (0.45) LPAR3LPAR2LPAR1BTN3A1
SCHEMBL2999226 0.73 BTN3A1 (0.45) LPAR3LPAR2LPAR1BTN3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113842459-B Inhibitor for pathological angiogenesis and application thereof 陈晓文 2023-01-06 CN disclosed
CN-113842459-A Inhibitor for pathological angiogenesis and application thereof 陈晓文 2021-12-28 CN disclosed