SCHEMBL2034053

SCHEMBL2034053

CC1(CCOP(=O)(O)OP(=O)(O)O)CO1

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 3/20 0.50
MVD P53602 4/20 0.41
GGPS1 O95749 4/20 0.36
FNTA P49354 3/20 0.36
PGGT1B P53609 2/20 0.36
FNTB P49356 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2034253 0.97 BTN3A1 (0.47) BTN3A1MVDGGPS1FNTAPGGT1B
SCHEMBL4946200 0.91 BTN3A1 (0.40) BTN3A1MVD
SCHEMBL2996800 0.90 BTN3A1 (0.47) BTN3A1MVDGGPS1FNTAPGGT1B
SCHEMBL4946206 0.89 BTN3A1 (0.39) BTN3A1MVDFNTAPGGT1BFNTB
SCHEMBL3005883 0.89 BTN3A1 (0.46) BTN3A1MVDGGPS1FNTAPGGT1B
SCHEMBL2995155 0.87 BTN3A1 (0.45) BTN3A1MVDGGPS1FNTAFNTB
SCHEMBL2993317 0.87 BTN3A1 (0.45) BTN3A1MVDGGPS1FNTAFNTB
SCHEMBL2999121 0.87 BTN3A1 (0.45) BTN3A1MVDGGPS1FNTAFNTB
SCHEMBL3004918 0.87 BTN3A1 (0.45) BTN3A1MVDGGPS1FNTAFNTB
SCHEMBL2999226 0.87 BTN3A1 (0.45) BTN3A1MVDGGPS1FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426052-B1 Compositions comprising interleukin-2 and gamma-delta T cell activator and uses thereof INNATE PHARMA (FR) 2009-09-02 EP claimed
US-20050196385-A1 Methods for producing gamma delta t cells INNATE PHARAMA (FR) 2005-09-08 US claimed
EP-1476540-A1 METHODS FOR PRODUCING GAMA DELTA T CELLS Innate Pharma (FR) 2004-11-17 EP claimed
EP-1426052-A1 Compositions comprising interleukin-2 and gamma-delta T cell activator and uses thereof Innate Pharma (FR) 2004-06-09 EP claimed
WO-2003070921-A1 METHODS FOR PRODUCING Ϝδ T CELLS INNATE PHARMA (FR) 2003-08-28 WO claimed
US-20110158954-A1 METHOD FOR PRODUCING GAMMA DELTA T CELL POPULATION TAKARA BIO INC. (JP) 2011-06-30 US disclosed
US-20100291118-A1 Class of Gamma Delta T Cells Activators and Use Thereof INNATE PHARMA (FR) 2010-11-18 US disclosed
US-20100254940-A1 Compositions and Methods for Regulating an Immune Response in a Subject INNATE PHARMA, S.A. (FR) 2010-10-07 US disclosed
US-7767842-B2 Class of γδ T cells activators and use thereof INNATE PHARMA SA (FR) 2010-08-03 US disclosed
US-20100189681-A1 Methods of Using Phosphoantigens Together with Interleukin-2 for the Treatment of Cancer INNATE PHARMA S.A. (FR) 2010-07-29 US disclosed
WO-2010049438-A2 IMPROVED METHODS OF USING PHOSPHOANTIGENS FOR THE TREATMENT OF DISEASES INNATE PHARMA (FR) 2010-05-06 WO disclosed
EP-1569656-B1 PHOSPHOANTIGENS FOR REGULATING AN IMMUNE RESPONSE INNATE PHARMA (FR) 2010-03-03 EP disclosed
EP-1569656-A2 PHOSPHOANTIGENS FOR REGULATING AN IMMUNE RESPONSE Innate Pharma (FR) 2005-09-07 EP disclosed
WO-2005077411-A2 COMPOSITION AND METHOD FOR THE TREATMENT OF CARCINOMA INNATE PHARMA (FR) 2005-08-25 WO disclosed
WO-2005054258-A2 NEW CLASS OF GAMMA DELTA T CELLS ACTIVATORS AND USE THEREOF INNATE PHARMA (FR) 2005-06-16 WO disclosed
WO-2004050096-A2 PHOSPHOANTIGENS FOR REGULATING AN IMMUNE RESPONSE INNATE PHARMA (FR) 2004-06-17 WO disclosed
EP-1426052-A1 Compositions comprising interleukin-2 and gamma-delta T cell activator and uses thereof Innate Pharma (FR) 2004-06-09 EP disclosed
EP-1109818-B1 PHOSPHOEPOXIDES, METHOD FOR MAKING SAME AND USES INST NAT SANTE RECH MED (FR) 2002-11-06 EP disclosed
EP-1109818-A1 PHOSPHOEPOXIDES, METHOD FOR MAKING SAME AND USES INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2001-06-27 EP disclosed
WO-2000012519-A1 PHOSPHOEPOXIDES, METHOD FOR MAKING SAME AND USES INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2000-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100254940-A1 Compositions and Methods for Regulating an Immune Response in a Subject IFNG, IL2, ICOS BTN3A1 288/4885MVD 4043/4885GGPS1 1850/4885
US-20050196385-A1 Methods for producing gamma delta t cells IFNG, IL2, ICOS BTN3A1 500/4885MVD 2813/4885GGPS1 1008/4885
US-20100189681-A1 Methods of Using Phosphoantigens Together with Interleukin-2 for the Treatment of Cancer IL2, IL2RA, CD4 BTN3A1 539/4885MVD 2950/4885GGPS1 1645/4885
US-20100291118-A1 Class of Gamma Delta T Cells Activators and Use Thereof CD4, IFNG, NFATC1 BTN3A1 224/4885MVD 3354/4885GGPS1 441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.