Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 3/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2896922 | 0.89 | FFAR2 (0.51) | FFAR2ABCB1 | |
| SCHEMBL475744 | 0.89 | FFAR2 (0.51) | FFAR2ABCB1 | |
| SCHEMBL30720983 | 0.89 | FFAR2 (0.51) | FFAR2ABCB1 | |
| SCHEMBL475745 | 0.89 | FFAR2 (0.51) | FFAR2ABCB1 | |
| SCHEMBL859599 | 0.89 | FFAR2 (0.51) | FFAR2ABCB1 | |
| SCHEMBL5156869 | 0.89 | FFAR2 (0.51) | FFAR2ABCB1 | |
| SCHEMBL6183606 | 0.89 | FFAR2 (0.51) | FFAR2ABCB1 | |
| SCHEMBL29040317 | 0.89 | FFAR2 (0.51) | FFAR2ABCB1 | |
| SCHEMBL310430 | 0.88 | KCNH2 (0.39) | PDE5ACHRM2CHRM1CHRM3 | |
| SCHEMBL839485 | 0.88 | KCNH2 (0.39) | PDE5ACHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114222728-A | Process for preparing alpha-carboxamide pyrrolidine derivatives | 生物基因公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-114026066-A | Process for preparing alpha-carboxamide pyrrolidine derivatives | 生物基因麻省公司 | 2022-02-08 | — | — | CN | disclosed |