Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EEF2K | O00418 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28705692 | 0.92 | NPC1 (0.43) | NPC1RAB9APOLBSMN1; SMN2GAA | |
| SCHEMBL28718835 | 0.92 | KDM4E (0.44) | LMNACYP2C9CYP2C19GAAFNTA | |
| SCHEMBL28708573 | 0.92 | LMNA (0.43) | NPC1RAB9APOLBSMN1; SMN2MAPT | |
| SCHEMBL28710574 | 0.91 | NPC1 (0.40) | NPC1RAB9APOLBSMN1; SMN2NPSR1 | |
| SCHEMBL28714867 | 0.91 | NPC1 (0.45) | NPC1RAB9AGAAFNTAFNTB | |
| SCHEMBL28714844 | 0.91 | NPC1 (0.45) | NPC1RAB9ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28710492 | 0.91 | LMNA (0.43) | NPC1RAB9APOLBSMN1; SMN2MAPT | |
| SCHEMBL28708516 | 0.91 | SMN1; SMN2 (0.45) | NPC1RAB9APOLBSMN1; SMN2MAPT | |
| SCHEMBL28714889 | 0.91 | SLC6A9 (0.43) | LMNACYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL28711974 | 0.90 | GAA (0.46) | NPC1RAB9ASMN1; SMN2LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113444005-B | Method for synthesizing novel glutaric acid compound from diaryl substituted non-activated olefin | 四川大学 | 2023-03-03 | — | — | CN | disclosed |
| CN-113444005-A | Method for synthesizing novel glutaric acid compound from diaryl substituted non-activated olefin | 四川大学 | 2021-09-28 | — | — | CN | disclosed |