Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28699487

N.Oc1ccccc1C(F)(F)F

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
TDP1 Q9NUW8 3/20 0.54
TSHR P16473 2/20 0.54
LMNA P02545 2/20 0.45
POLB P06746 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
NFKB1 P19838 2/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
CA2 P00918 2/20 0.45
KDM4E B2RXH2 1/20 0.45
CA12 O43570 1/20 0.45
GMNN O75496 1/20 0.45
EGFR P00533 1/20 0.45
FYN P06241 1/20 0.45
CA3 P07451 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPT P10636 1/20 0.45
MMP9 P14780 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29492110 0.97 ALDH1A1 (0.56) ALDH1A1TDP1TSHRLMNAPOLB
SCHEMBL69460 0.97 ALDH1A1 (0.56) ALDH1A1TDP1TSHRLMNAPOLB
Hydrochloric Acid SCHEMBL18955871 0.95 ALDH1A1 (0.54) ALDH1A1TDP1TSHRLMNAPOLB
SCHEMBL11348739 0.95 ALDH1A1 (0.54) ALDH1A1TDP1TSHRLMNAPOLB
Bromide SCHEMBL1854329 0.95 ALDH1A1 (0.54) ALDH1A1TDP1TSHRLMNAPOLB
SCHEMBL27510755 0.95 ALDH1A1 (0.54) ALDH1A1TDP1TSHRLMNAPOLB
SCHEMBL28955073 0.95 ALDH1A1 (0.54) ALDH1A1TDP1TSHRLMNAPOLB
Hydrochloric Acid SCHEMBL29242576 0.95 ALDH1A1 (0.54) ALDH1A1TDP1TSHRLMNAPOLB
Potassium SCHEMBL29898272 0.95 ALDH1A1 (0.54) ALDH1A1TDP1TSHRLMNAPOLB
Trimethylammonium SCHEMBL23035406 0.88 TDP1 (0.54) ALDH1A1TDP1TSHRLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110267963-B MAGL inhibitors H.隆德贝克有限公司 2022-04-01 CN disclosed