SCHEMBL69460

SCHEMBL69460

Oc1ccccc1C(F)(F)F

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
TDP1 Q9NUW8 3/20 0.56
TSHR P16473 3/20 0.56
CA2 P00918 3/20 0.47
LMNA P02545 2/20 0.47
POLB P06746 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
NFKB1 P19838 2/20 0.47
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47
CA12 O43570 1/20 0.47
GMNN O75496 1/20 0.47
EGFR P00533 1/20 0.47
FYN P06241 1/20 0.47
CA3 P07451 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAPT P10636 1/20 0.47
MMP9 P14780 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29492110 1.00 ALDH1A1 (0.56) ALDH1A1TDP1TSHRCA2LMNA
Hydrochloric Acid SCHEMBL18955871 0.97 ALDH1A1 (0.54) ALDH1A1TDP1TSHRCA2LMNA
Potassium SCHEMBL29898272 0.97 ALDH1A1 (0.54) ALDH1A1TDP1TSHRCA2LMNA
Bromide SCHEMBL1854329 0.97 ALDH1A1 (0.54) ALDH1A1TDP1TSHRCA2LMNA
SCHEMBL27510755 0.97 ALDH1A1 (0.54) ALDH1A1TDP1TSHRCA2LMNA
SCHEMBL11348739 0.97 ALDH1A1 (0.54) ALDH1A1TDP1TSHRCA2LMNA
Hydrochloric Acid SCHEMBL29242576 0.97 ALDH1A1 (0.54) ALDH1A1TDP1TSHRCA2LMNA
SCHEMBL28955073 0.97 ALDH1A1 (0.54) ALDH1A1TDP1TSHRCA2LMNA
Ammonia Solution, Strong SCHEMBL28699487 0.97 ALDH1A1 (0.54) ALDH1A1TDP1TSHRCA2LMNA
Trimethylammonium SCHEMBL23035406 0.91 TDP1 (0.54) ALDH1A1TDP1TSHRCA2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3299 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642784-A1 HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 PTC Therapeutics, Inc. (US) 2025-11-05 EP claimed
EP-4642772-A1 NLRP3 INFLAMMASOME INHIBITORS Astrazeneca AB (SE) 2025-11-05 EP claimed
WO-2025217091-A1 ODORANTS FOR FLUIDS, ODORIZED FLUIDS, METHODS, AND SYSTEMS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2025-10-16 WO claimed
WO-2025217099-A1 INHIBITORS FOR HYDROGEN EMBRITTLEMENT AND METHODS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2025-10-16 WO claimed
CN-119912339-A In the ilast group Process for the preparation of intermediates 浙江天宇药业股份有限公司 2025-05-02 CN claimed
CN-119717394-A Negative mixed phenolic resin composition and preparation method and application thereof 福建泓光半导体材料有限公司 2025-03-28 CN claimed
CN-119717393-A Negative phenolic resin composition and preparation method and application thereof 福建泓光半导体材料有限公司 2025-03-28 CN claimed
EP-4499638-A1 PYRIDO-[3,4-D]PYRIDAZINE AMINE DERIVATIVES USEFUL AS NLRP3 DERIVATIVES Ventus Therapeutics U.S., Inc. (US) 2025-02-05 EP claimed
EP-4419532-A1 FUSED BICYCLIC HETEROARYL COMPOUNDS USEFUL AS NLRP3 INHIBITORS F. Hoffmann-La Roche AG (CH) 2024-08-28 EP claimed
US-20240279237-A1 FUSED BICYCLIC HETEROARYL COMPOUNDS USEFUL AS NLRP3 INHIBITORS HOFFMANN-LA ROCHE INC. (US) 2024-08-22 US claimed
EP-0084136-B1 2-TRIFLUOROMETHYLPHENYL-(DI)-THIOPHOSPHORIC-ACID ESTER, PROCESS FOR ITS PREPARATION AND ITS USE AS A PESTICIDE BASF Aktiengesellschaft (DE) 1986-03-05 EP claimed
EP-0084136-A2 2-Trifluoromethylphenyl-(di)-thiophosphoric-acid ester, process for its preparation and its use as a pesticide BASF Aktiengesellschaft (DE) 1983-07-27 EP claimed
EP-0004447-B1 PREPARATION OF TRIFLUOROMETHYLPHENOLS AND NOVEL TRIFLUOROMETHYLPHENYL BENZYL ETHER INTERMEDIATES ELI LILLY AND COMPANY (US) 1981-12-02 EP claimed
EP-0000542-B1 PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYL PHENOLS BAYER AG (DE) 1981-07-15 EP claimed
US-4261846-A DITHIOPHOSPHATE OR ALKYLXANTHATE COLLECTOR; SUBSTITUTED BENZOTRIFLUORIDE DEPRESSANT UNITED STATES BORAX & CHEMICAL CORPORATION (US) 1981-04-14 US claimed
US-4259510-A TREATING A TRIFLUOROMETHYLHALOBENZENE WITH A HYDROXIDE FOLLOWED BY ETHERIFICATION WITH A HALONITROBENZENE ROHM AND HAAS COMPANY 1981-03-31 US claimed
US-4225731-A Process for the preparation of trifluoromethylphenols BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US claimed
US-4214710-A DEPRESSING CALCIUM FLUORIDE WITH AN HYDROXY-, AMINO-, AND/OR CARBOXYLIC ACID-SUBSTITUTED BENZOTRIFLUORIDE UNITED STATES BORAX & CHEMICAL CORPORATION (US) 1980-07-29 US claimed
EP-0004447-A2 Preparation of trifluoromethylphenols and novel trifluoromethylphenyl benzyl ether intermediates ELI LILLY AND COMPANY (US) 1979-10-03 EP claimed
US-3953490-A Preparation of (3-trifluoromethylphenoxy)(4-chlorophenyl)acetonitrile MERCK & CO., INC. (US) 1976-04-27 US claimed