Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 2/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL889064 | 0.80 | PTPN2 (0.60) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL18642102 | 0.80 | PTPN2 (0.60) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL18663457 | 0.80 | PTPN2 (0.60) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL29971632 | 0.79 | PTPN2 (0.71) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL29686111 | 0.79 | PTPN2 (0.71) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL1317618 | 0.79 | PTPN2 (0.71) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL30474534 | 0.78 | USP30 (0.42) | GPR119KMT2AMEN1USP30TP53 | |
| SCHEMBL13676224 | 0.77 | PTPN2 (0.68) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL18051092 | 0.76 | ALDH1A1 (0.65) | NPC1RAB9AABL1RIN1KMT2A | |
| SCHEMBL15686544 | 0.76 | PTPN2 (0.73) | PTPN2PTPN1PTPN6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354635-B | Pyrrolidine integrin regulator and application thereof | 清药同创(北京)药物研发中心有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-113354635-A | Pyrrolidine integrin regulator and application thereof | 清药同创(北京)药物研发中心有限公司 | 2021-09-07 | — | — | CN | disclosed |