Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14164989 | 0.87 | PDE4B (0.38) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL14165106 | 0.82 | PDE4A (0.44) | ALOX15ALOX12PDE4BADRB2ADRB3 | |
| SCHEMBL21709172 | 0.76 | BLM (0.47) | ALOX15ALOX12ADRB2ADRB3ADRB1 | |
| SCHEMBL1616464 | 0.72 | PDE4D (0.53) | PDE4BTSHRPDE4APDE4CPDE4D | |
| SCHEMBL15753781 | 0.72 | PDE4D (0.53) | PDE4BTSHRPDE4APDE4CPDE4D | |
| SCHEMBL14164833 | 0.72 | PDE4D (0.53) | PDE4BTSHRPDE4APDE4CPDE4D | |
| SCHEMBL30362076 | 0.72 | PDE4D (0.53) | PDE4BTSHRPDE4APDE4CPDE4D | |
| SCHEMBL9141282 | 0.69 | ALOX15 (0.50) | ALOX15ALOX12TSHRSMN1; SMN2AOC3 | |
| SCHEMBL15753320 | 0.68 | PDE4A (0.54) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL15753322 | 0.68 | PDE4A (0.54) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106946848-B | Derivatives of 1-phenyl-2-pyridylalkylalcohols as phosphodiesterase inhibitors | 奇斯药制品公司 | 2022-01-04 | — | — | CN | disclosed |