Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6849516 | 0.74 | EPHX1 (0.45) | EPHX2SIGMAR1P2RX7MEN1KMT2A | |
| SCHEMBL27742100 | 0.68 | MEN1 (0.31) | EPHX2MEN1KMT2ASLC22A2SLC47A1 | |
| SCHEMBL27968851 | 0.68 | MEN1 (0.36) | EPHX2P2RX7MEN1KMT2ASLC22A2 | |
| Amantadine SCHEMBL27831277 | 0.66 | GRIN2D (0.56) | SIGMAR1P2RX7GRIN2DGRIN3BGRIN1 | |
| SCHEMBL15657560 | 0.66 | ESR1 (0.54) | ESR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9721521 | 0.64 | HSD11B1 (0.42) | SIGMAR1P2RX7GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1733948 | 0.64 | EPHX2 (0.38) | EPHX2SIGMAR1P2RX7MEN1KMT2A | |
| SCHEMBL16541507 | 0.64 | ESR1 (0.52) | ESR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30195756 | 0.63 | SIGMAR1 (0.48) | EPHX2SIGMAR1P2RX7SLC22A2SLC47A1 | |
| SCHEMBL15009759 | 0.62 | MEN1 (0.41) | EPHX2P2RX7MEN1KMT2ASLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999261-A | O-dimethyl aromatic ring diphosphino ligand compound and synthetic method thereof | 浙江大学 | 2022-02-01 | — | — | CN | disclosed |