Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.50 |
| ▸ | TEK | Q02763 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712395 | 0.86 | MEN1 (0.58) | TGM2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28705879 | 0.79 | HSP90AA1 (0.47) | TGM2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL5430351 | 0.77 | CA1 (0.55) | MAPTLMNAALDH1A1NPSR1 | |
| SCHEMBL29174610 | 0.76 | MEN1 (0.52) | TGM2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL18520178 | 0.74 | TP53 (0.49) | KCNH2MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL15662405 | 0.74 | MEN1 (0.60) | TGM2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6612706 | 0.74 | TGM2 (0.40) | TGM2KCNH2MAPTLMNARAB9A | |
| SCHEMBL29174574 | 0.73 | MAPT (0.59) | TGM2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL22619812 | 0.73 | KMT2A (0.46) | TGM2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5629875 | 0.72 | CTSK (0.46) | TGM2KCNH2MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075139-A | Five-membered heteroaromatic ring compound and application thereof in medicines | 广东东阳光药业有限公司 | 2022-02-22 | — | — | CN | disclosed |