Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28700420 | 1.00 | TRPM8 (0.42) | TRPM8GPR139EPHX1PLA2G10PLA2G2A | |
| SCHEMBL28700452 | 0.88 | TRPM8 (0.43) | TRPM8GPR139EPHX1PLA2G10PLA2G2A | |
| SCHEMBL28700451 | 0.88 | TRPM8 (0.43) | TRPM8GPR139EPHX1PLA2G10PLA2G2A | |
| SCHEMBL28936580 | 0.84 | GPR139 (0.39) | TRPM8GPR139PDE2A | |
| SCHEMBL28706206 | 0.84 | TRPM8 (0.46) | TRPM8GPR139EPHX1 | |
| SCHEMBL28706208 | 0.84 | TRPM8 (0.46) | TRPM8GPR139EPHX1 | |
| SCHEMBL28712857 | 0.81 | TRPM8 (0.44) | TRPM8GPR139EPHX1 | |
| SCHEMBL28712855 | 0.81 | TRPM8 (0.44) | TRPM8GPR139EPHX1 | |
| SCHEMBL28715411 | 0.80 | TRPM8 (0.43) | TRPM8GPR139EPHX1 | |
| SCHEMBL28715408 | 0.80 | TRPM8 (0.43) | TRPM8GPR139EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206830-A | Alcohol derivatives as Kv7 potassium channel openers | H.隆德贝克有限公司 | 2022-03-18 | — | — | CN | disclosed |