Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20416924 | 1.00 | KMT2A (0.46) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL29396230 | 1.00 | KMT2A (0.46) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL2768221 | 0.78 | MAPT (0.40) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL20417208 | 0.78 | TOP2A (0.38) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL28700523 | 0.78 | SCN9A (0.40) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL16983093 | 0.78 | AAK1 (0.37) | RAB9ANPC1GAAMAPTALDH1A1 | |
| SCHEMBL2331441 | 0.77 | MAPT (0.45) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL2331444 | 0.77 | MAPT (0.45) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL28684445 | 0.77 | ACHE (0.37) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL20417009 | 0.77 | ALDH1A1 (0.36) | KMT2AMEN1GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110062757-B | Factor XIa inhibitors and uses thereof | 广东东阳光药业有限公司 | 2022-03-04 | — | — | CN | disclosed |