Oleic Acid

Oleic Acid

SCHEMBL28700604

CCCCCCCC/C=C\CCCCCCCC(=O)O.O=C(O)CC(O)C(=O)O

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CACNA1CCACNA1DCACNA1FCACNA1SDRD2HTR1BHTR1DHTR1F

The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.72
PPARD Q03181 5/20 0.72
PPARA Q07869 5/20 0.72
F7 P08709 5/20 0.72
F3 P13726 5/20 0.72
TERT O14746 3/20 0.72
PTPN1 P18031 3/20 0.72
HSD17B10 Q99714 3/20 0.72
FABP4 P15090 3/20 0.72
TOP1 P11387 3/20 0.72
MAPT P10636 2/20 0.72
BLM P54132 2/20 0.72
LMNA P02545 2/20 0.72
ALOX15 P16050 2/20 0.72
DUSP3 P51452 2/20 0.72
CYP19A1 P11511 2/20 0.72
PTGS1 P23219 2/20 0.72
NR4A2 P43354 2/20 0.72
SIRT6 Q8N6T7 2/20 0.72
PTPN7 P35236 2/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nervonic Acid SCHEMBL28437289 1.00 PPARG (0.72) PPARGPPARDPPARAF7F3
Stearic Acid SCHEMBL3379301 0.90 GPR84 (0.65) PPARGPPARDPPARAPTPN1HSD17B10
Behenic Acid SCHEMBL28358122 0.90 GPR84 (0.65) PPARGPPARDPPARAPTPN1HSD17B10
Octanoic Acid SCHEMBL31240956 0.90 GPR84 (0.65) PPARGPPARDPPARAPTPN1HSD17B10
Oleic Acid SCHEMBL14782676 0.89 PPARG (0.74) PPARGPPARDPPARAF7F3
Oleic Acid SCHEMBL14782679 0.89 PPARG (0.74) PPARGPPARDPPARAF7F3
Palmitic Acid SCHEMBL15066461 0.89 GPR84 (0.63) PPARGPPARDPPARAPTPN1HSD17B10
Palmitoleic Acid SCHEMBL15527702 0.88 PPARG (0.72) PPARGPPARDPPARAF7F3
Palmitoleic Acid SCHEMBL15527737 0.88 PPARG (0.72) PPARGPPARDPPARAF7F3
Palmitoleic Acid SCHEMBL15527740 0.88 PPARG (0.72) PPARGPPARDPPARAF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113373687-A Agent for treating artificial silk ear barrel and artificial silk ear barrel using same 三吉油脂株式会社 2021-09-10 CN disclosed