Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.65 |
| ▸ | PPARG | P37231 | 7/20 | 0.65 |
| ▸ | PPARD | Q03181 | 7/20 | 0.65 |
| ▸ | PPARA | Q07869 | 7/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TLR2 | O60603 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | FABP4 | P15090 | 2/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.65 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | PDE4A | P27815 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octanoic Acid SCHEMBL31240956 | 1.00 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Behenic Acid SCHEMBL28358122 | 1.00 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL15066461 | 0.98 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL28659566 | 0.93 | GPR84 (0.57) | GPR84PPARGPPARDPPARAHDAC11 | |
| Malic Acid SCHEMBL27725825 | 0.92 | SMN1; SMN2 (0.62) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL27713117 | 0.92 | FFAR4 (0.57) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL713824 | 0.92 | FFAR4 (0.57) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nervonic Acid SCHEMBL28437289 | 0.90 | PPARG (0.72) | PPARGPPARDPPARATSHRPTPN1 | |
| Stearic Acid SCHEMBL9580436 | 0.90 | FFAR1 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| Oleic Acid SCHEMBL28700604 | 0.90 | PPARG (0.72) | PPARGPPARDPPARATSHRPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024134610-A2 | ARTIFICIAL PROTEIN COMPOSITIONS | FORMO BIO GMBH (DE) | 2024-06-27 | — | — | WO | claimed |
| EP-0686025-B1 | TITANIUM DIOXIDE DISPERSIONS, COSMETIC COMPOSITIONS AND METHODS FOR USING THE SAME | ESTEE LAUDER INC (US) | 2003-09-10 | — | — | EP | claimed |
| CN-113164800-B | Detergent composition | 株式会社资生堂 | 2024-11-22 | — | — | CN | disclosed |
| US-12090133-B2 | Topical composition | THE MENTHOLATUM COMPANY (US) | 2024-09-17 | — | — | US | disclosed |
| CN-118415897-A | External skin barrier function repairing agent | 株式会社资生堂 | 2024-08-02 | — | — | CN | disclosed |
| WO-2024134610-A2 | ARTIFICIAL PROTEIN COMPOSITIONS | FORMO BIO GMBH (DE) | 2024-06-27 | — | — | WO | disclosed |
| CN-117777711-A | Method for producing resin molded body and resin composition | 旭化成株式会社 | 2024-03-29 | — | — | CN | disclosed |
| CN-111372474-B | Textured oil-in-water emulsions based on vegetable proteins | 雀巢产品有限公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-3723503-B1 | PLANT-PROTEIN BASED TEXTURIZED OIL-IN-WATER EMULSIONS | NESTLE SA (CH) | 2024-03-20 | — | — | EP | disclosed |
| CN-117598914-A | Water-in-oil type skin external composition | 株式会社资生堂 | 2024-02-27 | — | — | CN | disclosed |
| CN-117545460-A | Oil dispersion composition | 株式会社资生堂 | 2024-02-09 | — | — | CN | disclosed |
| EP-1550429-B1 | EXTERNAL PREPARATIONS FOR SKIN | SHISEIDO CO LTD (JP) | 2010-11-17 | — | — | EP | disclosed |
| CN-101466265-A | Alcohol-containing antimicrobial compositions having improved efficacy | DIAL CORP (US) | 2009-06-24 | — | — | CN | disclosed |
| CN-101460053-A | Methods and articles having a high antiviral and antibacterial efficacy | DIAL CORP (US) | 2009-06-17 | — | — | CN | disclosed |
| CN-101453890-A | Method of enhancing the control of viruses on skin | THR DIAL CORP (US) | 2009-06-10 | — | — | CN | disclosed |
| CN-101454012-A | Method for increased control of viruses on skin | THR DIAL CORP (US) | 2009-06-10 | — | — | CN | disclosed |
| CN-101453889-A | Composition and method for controlling the transmission of noroviruses | THR DIAL CORP (US) | 2009-06-10 | — | — | CN | disclosed |
| US-7445790-B2 | External preparations for skin | SHISEIDO COMPANY, LTD. (JP) | 2008-11-04 | — | — | US | disclosed |
| US-20050180931-A1 | External preparations for skin | SHISEIDO COMPANY, LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1550429-A1 | EXTERNAL PREPARATIONS FOR SKIN | SHISEIDO COMPANY, LTD. (JP) | 2005-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050180931-A1 | External preparations for skin | CUTA, HRH1, CYP24A1 | GPR84 37/4885PPARG 145/4885PPARD 492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.