Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 2/20 | 0.45 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28700696 | 1.00 | CNR2 (0.48) | CNR2MMP1MDM4MDM2KIF11 | |
| SCHEMBL28710172 | 0.81 | ANPEP (0.46) | CNR2MMP1ANPEPGPR88ATM | |
| SCHEMBL28709110 | 0.81 | ANPEP (0.46) | CNR2MMP1ANPEPGPR88ATM | |
| SCHEMBL28934074 | 0.80 | HDAC3 (0.51) | CNR2MMP1ANPEPGPR88ATM | |
| SCHEMBL28934073 | 0.80 | HDAC3 (0.51) | CNR2MMP1ANPEPGPR88ATM | |
| SCHEMBL28709129 | 0.77 | CNR2 (0.58) | CNR2ANPEPGPR88ATMHDAC1 | |
| SCHEMBL28709128 | 0.77 | CNR2 (0.58) | CNR2ANPEPGPR88ATMHDAC1 | |
| SCHEMBL5173278 | 0.74 | NPSR1 (0.49) | CNR2MMP1ATMMMP2MMP3 | |
| SCHEMBL29449812 | 0.73 | ANPEP (0.54) | MMP1MDM4MDM2ANPEPMMP3 | |
| SCHEMBL28785765 | 0.71 | HDAC4 (0.70) | CNR2GPR88HDAC1HDAC7CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181116-A | D-amino acid derivative aminopeptidase N inhibitor and preparation method and application thereof | 山东中医药大学 | 2022-03-15 | — | — | CN | disclosed |